产品货号：
Z16161
中文名称：
FOXO3A/FOXO3抗体
英文名称：
Anti-FOXO3A/FOXO3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FOXO3A/FOXO3 Antibody |
| 指标别名 | AF6q21;AF6q21 protein;FKHRL1;FKHRL1P2;forkhead box O3;Forkhead box protein O3;FOXO2;FOXO3;FOXO3A |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC |
| 基因名称 | FOXO3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human FOXO3A recombinant protein (Position:Q471-G673).Human FOXO3A shares 97% amino acid (aa) sequence identity with mouse FOXO3A. |
| 实际分子量 | 90KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Forkhead box O3,also known as FKHRL1 or FOXO3a,is a human protein encoded by the FOXO3 gene.FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain.It is mapped to 6q21.This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death,such as Bim and PUMA,or downregulation of anti-apoptotic proteins such as FLIP.In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span.In addition,it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD. |
| Uniprot ID | O43524 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | forkhead box O3 |
| 蛋白名全称 | Forkhead box protein O3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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